Prothrombin Gene G ₂₀₂₁₀ →A Transition Is a Risk Factor for Cerebral Venous Thrombosis

Background and Purpose —It has been recently reported that a G→A transition at nucleotide position 20210 in the 3′-untranslated region of the prothrombin gene is associated with elevated plasma prothrombin levels and an increased risk of deep venous thrombosis. To date, it is unknown whether this polymorphism also represents a risk factor for cerebral venous thrombosis (CVT). Methods —Venous blood samples were collected from 45 patients with CVT...