Coexistence of multiple endocrine neoplasia type 1 and type 2 in a large Italian family
Abstract
To describe the coexistence of mutations of both the multiple endocrine neoplasia type 1 (MEN1) and type 2 (MEN2) genes in a large Italian family and evaluate if it could be associated with more aggressive clinical manifestations of the two syndromes. Blood samples were obtained for genetic and biochemical analyses. The RET gene exons (8, 10, 11, 13, 14, 15, 16, 18) and the MEN1 coding regions, including the exon–intron boundaries, were...
Paper Details
Title
Coexistence of multiple endocrine neoplasia type 1 and type 2 in a large Italian family
Published Date
Jun 17, 2011
Journal
Volume
40
Issue
3
Pages
481 - 485
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