Course and prognosis of anti-basement membrane antibody (anti-BM-Ab)-mediated disease: report of 35 cases

Anti-basement membrane antibody (antiBM Ab) mediated disease is reported to be a rare disorder frequently leading to severe deterioration of renal function. It was our purpose to work out parameters necessary to predict the outcome reliably and to examine, who will benefit most from therapy. Data from 35 patients were evaluated retrospectively. Diagnosis was based on the detection of linear IgG staining (n=28) along the glomerular basement...