Original paper

Large-scale genomics unveil polygenic architecture of human cortical surface area

Volume: 6, Issue: 1
Published: Jul 20, 2015
Abstract
Little is known about how genetic variation contributes to neuroanatomical variability, and whether particular genomic regions comprising genes or evolutionarily conserved elements are enriched for effects that influence brain morphology. Here, we examine brain imaging and single-nucleotide polymorphisms (SNPs) data from ∼2,700 individuals. We show that a substantial proportion of variation in cortical surface area is explained by additive...
Paper Details
Title
Large-scale genomics unveil polygenic architecture of human cortical surface area
Published Date
Jul 20, 2015
Volume
6
Issue
1
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