Original paper

Divergent Roles of PAX2 in the Etiology and Progression of Ovarian Cancer

Volume: 8, Issue: 12, Pages: 1163 - 1173
Published: Dec 1, 2015
Abstract
PAX2 is an essential transcription factor for development. Aberrant PAX2 expression in adult tissues is associated with carcinogenesis and experimental evidence shows that PAX2 generally exhibits oncogenic properties. Although PAX2 is not expressed in normal ovaries, it is highly expressed in low malignant potential and low-grade epithelial ovarian tumors, suggesting that PAX2 induction in ovarian surface epithelium (OSE) may contribute to...
Paper Details
Title
Divergent Roles of PAX2 in the Etiology and Progression of Ovarian Cancer
Published Date
Dec 1, 2015
Volume
8
Issue
12
Pages
1163 - 1173
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