Subregional Basal Forebrain Atrophy in Alzheimer's Disease: A Multicenter Study
Abstract
Histopathological studies in Alzheimer's disease (AD) suggest severe and region-specific neurodegeneration of the basal forebrain cholinergic system (BFCS). Here, we studied the between-center reliability and diagnostic accuracy of MRI-based BFCS volumetry in a large multicenter data set, including participants with prodromal (n = 41) or clinically manifest AD (n = 134) and 148 cognitively healthy controls. Atrophy was determined using...
Paper Details
Title
Subregional Basal Forebrain Atrophy in Alzheimer's Disease: A Multicenter Study
Published Date
Apr 23, 2014
Volume
40
Issue
3
Pages
687 - 700
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