Collagen scaffolds as a tool for understanding the biological effect of silicates
Abstract
Dietary silicon is essential in the maintenance of bone and cartilage. However, the mechanism by which silicon, in the form of silicates, triggers a biological response has never been uncovered. Here we demonstrate the incorporation of orthosilicic acid (Si(OH)4), the form of silicon in the body, within collagen scaffolds for use as an in vitro platform to identify key genes affected by silicates. Ice-templated collagen–silicate scaffolds,...
Paper Details
Title
Collagen scaffolds as a tool for understanding the biological effect of silicates
Published Date
Oct 1, 2015
Journal
Volume
157
Pages
176 - 179
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History