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Review paper

Asymmetric Michael Addition in Synthesis of β-Substituted GABA Derivatives

Volume: 27, Issue: 12, Pages: 3797 - 3797
Published: Jun 13, 2022
Abstract
γ-Aminobutyric acid (GABA) represents one of the most prolific structural units widely used in the design of modern pharmaceuticals. For example, β-substituted GABA derivatives are found in numerous neurological drugs, such as baclofen, phenibut, tolibut, pregabalin, phenylpiracetam, brivaracetam, and rolipram, to mention just a few. In this review, we critically discuss the literature data reported on the preparation of substituted GABA...
Paper Details
Title
Asymmetric Michael Addition in Synthesis of β-Substituted GABA Derivatives
Published Date
Jun 13, 2022
Journal
Volume
27
Issue
12
Pages
3797 - 3797
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