Internal medicine

Therapeutic endoscopy

Meta-analysis

Odds ratio

Surgery

Political science

Subgroup analysis

Diagnostic odds ratio

MEDLINE

Capsule endoscopy

Endoscopy

Enteroscopy

Medicine

Gastrointestinal Endoscopy

Small-bowel capsule endoscopy (SBCE) and device-assisted enteroscopy (DAE) are essential in obscure GI bleeding (OGIB) management. However, the best timing for such procedures remains unknown. This meta-analysis aimed to compare, for the first time, diagnostic and therapeutic yields, detection of active bleeding and vascular lesions, recurrent bleeding, and mortality of “early” versus “nonearly” SBCE and DAE.

Diagnostic and therapeutic yields of early capsule endoscopy and device-assisted enteroscopy in the setting of overt GI bleeding: a systematic review with meta-analysis