Lung transplant recipients with idiopathic pulmonary fibrosis have impaired alloreactive immune responses

Volume: 41, Issue: 5, Pages: 641 - 653
Published: May 1, 2022
Abstract
Telomere dysfunction is associated with idiopathic pulmonary fibrosis (IPF) and worse outcomes following lung transplantation. Telomere dysfunction may impair immunity by upregulating p53 and arresting proliferation, but its influence on allograft-specific immune responses is unknown. We hypothesized that subjects undergoing lung transplantation for IPF would have impaired T cell proliferation to donor antigens.We analyzed peripheral blood...
Paper Details
Title
Lung transplant recipients with idiopathic pulmonary fibrosis have impaired alloreactive immune responses
Published Date
May 1, 2022
Volume
41
Issue
5
Pages
641 - 653
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