Journal of Heart and Lung Transplantation
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#2Chad MaoH-Index: 3
#3Lydia WrightH-Index: 3
Last. Joshua Sparks (University of Louisville)H-Index: 3
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Background null There is wide variability in the timing of heart transplant (HTx) after pediatric VAD implant. While some centers wait months before listing for HTx, others accept donor heart offers within days of VAD surgery. We sought to determine if HTx within 30 days versus ≥ 30 after VAD impacts post-HTx outcomes. null Methods null Children on VAD pre-HTx were extracted from the Pediatric Heart Transplant Study database. The primary endpoints were post-HTx length of hospital stay (LOS) and ...
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#1Jae Hee Seol (Yonsei University)
#2Ah Young Kim (Yonsei University)H-Index: 3
Last. Jo Won Jung (Yonsei University)H-Index: 10
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Abstract null null We report a case of rapidly progressed cardiac remodeling in a child with hypertrophic cardiomyopathy. Three and a half years after the diagnosis of hypertrophic cardiomyopathy, arrhythmia and heart failure due to aggravated septal hypertrophy and left ventricle apical aneurysm progressed, and a heart transplant was performed.
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#1Chelsea E. Halprin (Cedars-Sinai Medical Center)
#2Lawrence S.C. Czer (Cedars-Sinai Medical Center)H-Index: 60
Last. D. Megna (Cedars-Sinai Medical Center)H-Index: 2
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Background null Mechanical null circulatory support null null null device (MCSD) patients with positive heparin-induced thrombocytopenia (HIT) screening pose a unique challenge, as clinicians must make rapid decisions about their null anticoagulation null null and whether they can safely undergo null cardiopulmonary bypass . We identified screening practices at our institution and other institutions nationwide that differed from American Society of null null null Hematology null (ASH) guidelines...
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#1Jan Bogaert (Katholieke Universiteit Leuven)H-Index: 76
#2Guido Claessen (Katholieke Universiteit Leuven)H-Index: 16
Last. Rolf Symons (Katholieke Universiteit Leuven)H-Index: 17
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BACKGROUND Right heart failure (RHF) in pulmonary hypertension (PH) patients is manifested by increased right atrial (RA) pressure. We hypothesized liver relaxation times measured at cardiovascular magnetic resonance (CMR) can be used to noninvasively assess increased right-sided filling pressure. METHODS Forty-five consecutive patients, that is, 37 PH patients and 8 chronic thromboembolic pulmonary disease patients without PH underwent right heart catheterization and CMR. CMR findings were comp...
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#1Thomas CascinoH-Index: 1
#2Josef Stehlik (UM: University of Michigan)
Last. Supriya ShoreH-Index: 10
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Abstract null null Background null The United States National Organ Procurement Transplant Network (OPTN) implemented changes to the adult heart allocation system to reduce waitlist mortality by improving access for those at greater risk of pre-transplant death, including patients on short-term mechanical circulatory support (sMCS). While sMCS increased, it is unknown whether the increase occurred equitably across centers. null null null Methods null The OPTN database was used to assess changes ...
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Introduction null null Patients with ambulatory advanced heart failure (HF) are increasingly considered for durable mechanical null circulatory support null (MCS) and null null heart transplantation null and their effective triage requires careful assessment of the clinical trajectory. null null null Methods null REVIVAL, a prospective, observational study, enrolled 400 ambulatory advanced HF patients from 21 MCS/transplant centers in 2015-2016. Study design included a clinical re-assessment of ...
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Background null In human lung transplant recipients, a decline in club cell secretory protein (CCSP) in bronchoalveolar lavage fluid has been associated with chronic lung allograft dysfunction (CLAD) as well as the induction of exosomes and immune responses that lead to CLAD. However, the mechanisms by which CCSP decline contributes to CLAD remain unknown. null Methods null To define the mechanisms leading to CCSP decline and chronic rejection, we employed two mouse models: 1) chronic rejection ...
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#1Sandhya Bansal (St. Joseph's Hospital and Medical Center)H-Index: 12
#2A. Arjuna (St. Joseph's Hospital and Medical Center)H-Index: 2
Last. Thalachallour Mohanakumar (St. Joseph's Hospital and Medical Center)H-Index: 18
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Background null Chronic lung allograft dysfunction in lung transplant recipients (LTxRs) has 2 phenotypes: obstructive bronchiolitis obliterans syndrome (BOS) and restrictive allograft syndrome (RAS). Our goal was to define distinct immunologic markers of exosomes from LTxRs with BOS or RAS. null null null Methods null Plasma was collected from LTxRs with BOS (n = 18), RAS (n = 13), and from stable LTxRs (n = 5). Antibodies to lung self-antigens (SAgs) were determined by ELISA. Exosomes were iso...
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#1D. Marshall Brinkley (VUMC: Vanderbilt University Medical Center)H-Index: 7
#2Li Wang (VUMC: Vanderbilt University Medical Center)
Last. Michael S. Kiernan (Tufts Medical Center)H-Index: 28
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BACKGROUND Inhibition of the renin angiotensin aldosterone system (RAAS) improves survival and reduces adverse cardiac events in heart failure with reduced ejection fraction, but the benefit is not well-defined following left ventricular assist device (LVAD). METHODS We analyzed the ISHLT IMACS registry for adults with a primary, continuous-flow LVAD from January 2013 to September 2017 who were alive at postoperative month 3 without a major adverse event, and categorized patients according to tr...
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#1Ross M. Reul (BCM: Baylor College of Medicine)H-Index: 1
#2Gabriel Loor (BCM: Baylor College of Medicine)H-Index: 11
Last. Abbas Rana (BCM: Baylor College of Medicine)H-Index: 25
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ABSTRACT null null Background null The demand for donor lungs continues to outpace the supply, yet nearly 75% of donor lungs intended for lung transplantation are discarded. null null null Methods null We reviewed all donation after brain death organ donors listed within the UNOS Deceased Donor Database between 2005 and 2020. Univariable and multivariable analyses were run on the training set (n=69,355) with the primary outcome defined as lung discard, and the results were used to create a disca...
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