Journal of Heart and Lung Transplantation
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#1A. PerezH-Index: 2
#2Lorriana E. LeardH-Index: 19
#1Stephen J. Dolgner (Boston Children's Hospital)
#2Vidang P. Nguyen (Providence St. Vincent Medical Center)
Last. Todd F. Dardas (UW: University of Washington)H-Index: 17
view all 4 authors...
BACKGROUND Heart transplant programs and regulatory entities require highly accurate performance metrics to support internal quality improvement activities and national oversight of transplant programs, respectively. We assessed the accuracy of publicly reported performance measures. METHODS We used the United Network for Organ Sharing registry to study patients who underwent heart transplantation between January 1, 2016 and June 30, 2018. We used tests of calibration to compare the observed rat...
#1Errol L. Bush (JHU: Johns Hopkins University)H-Index: 17
#2Aravind Krishnan (JHU: Johns Hopkins University)H-Index: 3
Last. Christian A. Merlo (JHU: Johns Hopkins University)H-Index: 31
view all 15 authors...
Abstract null null Background null The purpose of this study was to evaluate outcomes in people with cystic fibrosis (CF) who underwent lung transplant (LT) at a transplant center with an accredited Cystic Fibrosis Care Center (CFCC) in the United States. null null null Methods null We reviewed the Scientific Registry of Transplant Recipients for all adult patients with CF who received a first-time LT from 2005 to 2018. The primary outcome was graft failure. Unadjusted Kaplan-Meier analysis and ...
#1Ping Wang (UCSF: University of California, San Francisco)H-Index: 3
#2Joey Leung (UCSF: University of California, San Francisco)H-Index: 1
Last. John R. Greenland (UCSF: University of California, San Francisco)H-Index: 17
view all 12 authors...
Abstract null null Background: Telomere dysfunction is associated with idiopathic pulmonary fibrosis (IPF) and worse outcomes following lung transplantation. Telomere dysfunction may impair immunity by upregulating p53 and arresting proliferation, but its influence on allograft-specific immune responses is unknown. We hypothesized that subjects undergoing lung transplantation for IPF would have impaired T-cell proliferation to donor antigens. null Methods: We analyzed peripheral blood mononuclea...
#1J. Lukac (UH: University of Helsinki)H-Index: 1
#2Kishor Dhaygude (UH: University of Helsinki)H-Index: 8
Last. Karl B. Lemström (UH: University of Helsinki)H-Index: 29
view all 10 authors...
ABSTRACT null null Background null The pathophysiological changes related to brain death may affect the quality of the transplanted organs and expose the recipients to risks. We probed systemic changes reflected in donor plasma proteome and investigated their relationship to heart transplant outcomes. null null null Methods null Plasma samples from brain-dead multi-organ donors were analyzed by label-free protein quantification using high-definition mass spectrometry. Unsupervised and supervised...
#1Hoong Sern Lim (UHB: University Hospitals Birmingham NHS Foundation Trust)H-Index: 3
#2Steven M. Shaw (University of Manchester)H-Index: 14
Last. Mandeep R. Mehra (BWH: Brigham and Women's Hospital)H-Index: 72
view all 6 authors...
Abstract null null Aim: The clinical and cost-effectiveness of left ventricular assist device (LVAD) therapy for patients with advanced heart failure (HF) who are ineligible for heart transplantation is debated in UK. This study develops an indirect comparison between the fully magnetically levitated HeartMate 3 (HM 3) LVAD and medical therapy (MT) to evaluate expected clinical and cost-effectiveness in the UK National Health Service (NHS) context. null Methods: We performed an economic analysis...
#1Conway, Jennifer, Auerbach, Scott R. (University of Alberta)
#2Marc E. Richmond (CHONY: Morgan Stanley Children's Hospital)H-Index: 22
Last. James K. Kirklin (UAB: University of Alabama at Birmingham)H-Index: 77
view all 4 authors...
ABSTRACT null null Background: Reports focused on adult heart transplant (HTx) recipients with COVID-19 suggest an increased risk of severe disease, however; it is unclear if this holds true for pediatric HTx patients, given the typically milder course of illness in children in general with COVID-19. We sought to rapidly implement a system for multi-center data collection on pediatric HTx candidates and recipients, with the aim of describing the patient population and infection related outcomes....
#1Jong-Chan Youn (Catholic University of Korea)H-Index: 2
#2Xiaohai Zhang (Cedars-Sinai Medical Center)H-Index: 6
Last. Jon A. Kobashigawa (Cedars-Sinai Medical Center)H-Index: 62
view all 15 authors...
Abstract null null Background null Sensitization, defined as the presence of circulating antibodies, presents challenges, particularly in patients undergoing heart transplantation (HTx) bridged with durable mechanical circulatory support (MCS). We aimed to investigate the post-transplantation outcomes of sensitized MCS patients. null null null Methods null Among 889 consecutively enrolled heart transplant (HTx) recipients between 2010 and 2018, 86 (9.7%) sensitized MCS patients (Group A) were co...
#1Luke Benvenuto (CU: Columbia University)H-Index: 9
#2Michaela R. Anderson (CU: Columbia University)H-Index: 7
Last. Selim M. Arcasoy (CU: Columbia University)H-Index: 36
view all 14 authors...
Abstract null null Background null : The primary lung allocation unit was expanded from the donation service area to a 250-mile radius in 2017. Prior to the change, geographic disparities in donor lung availability impacted waitlist outcomes. We sought to determine if the new allocation system improved these disparities. null null null Methods null : We conducted a retrospective cohort study comparing the 2-year period before and after the change. Donor lung availability was defined as the ratio...
#1Brian Hsi (Houston Methodist)H-Index: 1
#2D.T. Joseph (Houston Methodist)H-Index: 3
Last. Ju H. Kim (Houston Methodist)H-Index: 1
view all 8 authors...
ABSTRACT null null Risk assessment for early, severe right heart failure (RHF) after LVAD implantation remains imperfect. We sought to define the differences in RV adaptation and load after axillary Impella support between patients who experienced RHF and those who did not. Seventeen of 18 patients included were deemed intermediate or high risk for RHF by EUROMACS-RHF score. Before Impella insertion, RV adaptation parameters (RAP, RAP:PCWP, PAPi) were worse in the non-RHF group compared to the R...
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