Macrophages in ovarian cancer and their interactions with monoclonal antibody therapies
Abstract
The unmet clinical need for effective treatments in ovarian cancer has yet to be addressed using monoclonal antibodies (mAbs), which have largely failed to overcome tumour-associated immunosuppression, restrict cancer growth, and significantly improve survival. In recent years, experimental mAb design has moved away from solely targeting ovarian tumours and instead sought to modulate the wider tumour microenvironment (TME). Tumour-associated...
Paper Details
Title
Macrophages in ovarian cancer and their interactions with monoclonal antibody therapies
Published Date
Nov 22, 2021
Volume
209
Issue
1
Pages
4 - 21
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