Nicotinamide and Pyruvate for Neuroenhancement in Open-Angle Glaucoma

Open-angle glaucoma may continue to progress despite significant lowering of intraocular pressure (IOP). Preclinical research has suggested that enhancing mitochondrial function and energy production may enhance retinal ganglion cell survival in animal models of glaucoma, but there is scant information on its effectiveness in a clinical setting.To test the hypothesis that a combination of nicotinamide and pyruvate can improve retinal ganglion...