Original paper
Impact of FKS 1 genotype on echinocandin in-vitro susceptibility in Candida auris and in -vivo response in a murine model of infection
Abstract
Objectives: Echinocandins are frontline antifungal agents in the management of invasive infections due to multi-drug resistant Candida auris. The study aimed to evaluate echinocandin resistance in C. auris isolates of multicentric origin, identify the resistance mechanism, and analyze the pharmacodynamic response to caspofungin in a neutropenic mouse model of infection. Methods: A total of 199 C. auris isolates originating from thirty centres...
Paper Details
Title
Impact of FKS 1 genotype on echinocandin in-vitro susceptibility in Candida auris and in -vivo response in a murine model of infection
Published Date
Nov 15, 2021
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Notes
History