Original paper
Ag(I)‐Catalyzed/Acid‐Mediated Cascade Cyclization of ortho‐Alkynylaryl‐1,3‐dicarbonyls to Access Arylnaphthalenelactones and Furanonaphthol Libraries via Aryl‐Disengagement
Abstract
ortho-Alkynylarylketone derivatives were employed as key precursors for a one-pot synthesis of arylnaphthalenelactone and furanonaphthol libraries. In this work, we discovered a cost-effective protocol to prepare arylnaphthalenelactones in one-pot using inexpensive starting material, malonate ester, which was conveniently functionalized leading to a variety of structures. Moreover, we also found an unexpected oxy-dearylation reaction which could...
Paper Details
Title
Ag(I)‐Catalyzed/Acid‐Mediated Cascade Cyclization of ortho‐Alkynylaryl‐1,3‐dicarbonyls to Access Arylnaphthalenelactones and Furanonaphthol Libraries via Aryl‐Disengagement
Published Date
Nov 26, 2021
Journal
Volume
17
Issue
1
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Notes
History