Characterization of nanoparticles using coupled gel immobilization and label-free optical imaging

Accurate quantification of number concentration of nanoparticles (NPs) is critical for their biomedical and catalytic applications. We developed a novel NP analysis platform based on coupled gel immobilization and a three-dimensional (3D) scattered light imaging (SLI) platform. This imaging-based technique enables high-throughput analysis of silver nanoparticles (AgNPs) at single-particle level without the need for particle labeling or...