Ion concentrations in cerebrospinal fluid in wakefulness, sleep and sleep deprivation in healthy humans
Abstract
Sleep is controlled by a circadian rhythmicity, via a reduction of arousal-promoting neuromodulatory activity, and by accumulation of somnogenic factors in the interstitial fluid of the brain. Recent experiments in mice suggest that a reduced neuronal excitability caused by a reduced concentration of potassium in the brain, concomitant with an increased concentration of calcium and magnesium, constitutes an important mediator of sleep. In the...
Paper Details
Title
Ion concentrations in cerebrospinal fluid in wakefulness, sleep and sleep deprivation in healthy humans
Published Date
Nov 17, 2021
Journal
Volume
31
Issue
3
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