Original paper
The distinct responsiveness of cytokeratin 19-positive hepatocellular carcinoma to regorafenib
Abstract
Cytokeratin 19-positive (CK19+) hepatocellular carcinoma (HCC) is an aggressive subtype characterized by early recurrence and chemotherapy tolerance. However, there is no specific therapeutic option for CK19+ HCC. The correlation between tumor recurrence and expression status of CK19 were studied in 206 patients undergoing liver transplantation for HCC. CK19-/+ HCC cells were isolated to screen effective antitumor drugs. The therapeutic effects...
Paper Details
Title
The distinct responsiveness of cytokeratin 19-positive hepatocellular carcinoma to regorafenib
Published Date
Nov 16, 2021
Journal
Volume
12
Issue
12
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Notes
History