Optimization of non-coding regions for a non-modified mRNA COVID-19 vaccine
Abstract
The CVnCoV (CureVac) mRNA vaccine for severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) was recently evaluated in a phase 2b/3 efficacy trial in humans1. CV2CoV is a second-generation mRNA vaccine containing non-modified nucleosides but with optimized non-coding regions and enhanced antigen expression. Here we report the results of a head-to-head comparison of the immunogenicity and protective efficacy of CVnCoV and CV2CoV in...
Paper Details
Title
Optimization of non-coding regions for a non-modified mRNA COVID-19 vaccine
Published Date
Nov 18, 2021
Journal
Volume
601
Issue
7893
Pages
410 - 414
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Notes
History