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Review paper

The Kynurenine Pathway in Acute Kidney Injury and Chronic Kidney Disease

Volume: 52, Issue: 10-11, Pages: 771 - 787
Published: Jan 1, 2021
Abstract
The kynurenine pathway (KP) is the major catabolic pathway for tryptophan degradation. The KP plays an important role as the sole de novo nicotinamide adenine dinucleotide (NAD+) biosynthetic pathway in normal human physiology and functions as a counter-regulatory mechanism to mitigate immune responses during inflammation. Although the KP has been implicated in a variety of disorders including Huntington's disease, seizures, cardiovascular...
Paper Details
Title
The Kynurenine Pathway in Acute Kidney Injury and Chronic Kidney Disease
Published Date
Jan 1, 2021
Volume
52
Issue
10-11
Pages
771 - 787
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