Original paper
Activation of Crtc2/Creb1 in skeletal muscle enhances weight loss during intermittent fasting.
Abstract
The Creb-Regulated Transcriptional Coactivator (Crtc) family of transcriptional coregulators drive Creb1-mediated transcription effects on metabolism in many tissues, but the in vivo effects of Crtc2/Creb1 transcription on skeletal muscle metabolism are not known. Skeletal muscle-specific overexpression of Crtc2 (Crtc2 mice) induced greater mitochondrial activity, metabolic flux capacity for both carbohydrates and fats, improved glucose...
Paper Details
Title
Activation of Crtc2/Creb1 in skeletal muscle enhances weight loss during intermittent fasting.
Published Date
Dec 1, 2021
Journal
Volume
35
Issue
12
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Notes
History