Phase-dependent local brain states determine the impact of image-guided TMS on motor network EEG synchronization.

Key points null Synchronized TMS pulses with pre-defined brain oscillatory phases allows to evaluate the impact of brain states on TMS effects. TMS pulses over M1 at the negative peak of μ-frequency band induces higher phase-lock synchronization with interconnected contralateral homologous regions. Cortico-cortical synchronization changes are linearly predicted by the fiber density and cross-section of the white matter tract that connect the two...