Original paper
The Future of Uncertainty Factors With In Vitro Studies Using Human Cells
Abstract
New approach methodologies (NAMs), including in vitro toxicology methods such as human cells from simple cell cultures to 3D and organ-on-a-chip models of human lung, intestine, liver, and other organs, are challenging the traditional “norm” of current regulatory risk assessments. Uncertainty Factors continue to be used by regulatory agencies to account for perceived deficits in toxicology data. With the expanded use of human cell NAMs, the...
Paper Details
Title
The Future of Uncertainty Factors With In Vitro Studies Using Human Cells
Published Date
Nov 10, 2021
Journal
Volume
186
Issue
1
Pages
12 - 17
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History