Original paper
CFTR limits F‐actin formation and promotes morphological alignment with flow in human lung microvascular endothelial cells
Abstract
Micro- and macrovascular endothelial dysfunction in response to shear stress has been observed in cystic fibrosis (CF), and has been associated with inflammation and oxidative stress. We tested the hypothesis that the cystic fibrosis transmembrane conductance regulator (CFTR) regulates endothelial actin cytoskeleton dynamics and cellular alignment in response to flow. Human lung microvascular endothelial cells (HLMVEC) were cultured with either...
Paper Details
Title
CFTR limits F‐actin formation and promotes morphological alignment with flow in human lung microvascular endothelial cells
Published Date
Dec 1, 2021
Journal
Volume
9
Issue
23
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Notes
History