Loss of ATP5A1 enhances proliferation and predicts poor prognosis of colon adenocarcinoma

ATP Synthase F1 Subunit Alpha (ATP5F1A), also named as ATP5A1, is a subunit of mitochondrial ATP synthase. Dysregulated expression of ATP5A1 has been reported in several malignancies, nevertheless it showed either oncogenic or tumor-suppressing roles in different cancer types. Here we aimed to initially investigate the expression and role of ATP5A1 in colon adenocarcinoma.We firstly evaluated the transcription and mRNA levels of ATP5A1 using...