Effect of sex and food on the pharmacokinetics of different classes of BCS drugs in rats after cassette administration
Abstract
The cassette dosing technique is employed in the drug discovery stage of non-clinical studies to obtain pharmacokinetic data from multiple drug candidates in a single experiment. The objective of the current investigation was to evaluate the effect of sex and food on the selected pharmacokinetic parameters of four biopharmaceutical classification system (BCS) drugs (BCS-I: propranolol, BCS-II: diclofenac, BCS-III: atenolol, and BCS-IV:...
Paper Details
Title
Effect of sex and food on the pharmacokinetics of different classes of BCS drugs in rats after cassette administration
Published Date
Dec 1, 2021
Volume
610
Pages
121221 - 121221
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