Original paper

Effects of dose loading conditions and device geometry on the transport and aerosolization in dry powder inhalers: A simulation study

Volume: 610, Pages: 121219 - 121219
Published: Dec 1, 2021
Abstract
The transport and aerosolization of particles are studied in several different dry powder inhaler geometries via Computational Fluid Dynamics-Discrete Element Method (CFD-DEM) simulations. These simulations combine Large Eddy Simulation of gas with Discrete Element Model simulation of all the carrier particles and a representative subset of the active pharmaceutical ingredient (API) particles. The purpose of the study is to probe the dominant...
Paper Details
Title
Effects of dose loading conditions and device geometry on the transport and aerosolization in dry powder inhalers: A simulation study
Published Date
Dec 1, 2021
Volume
610
Pages
121219 - 121219
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