Cabazitaxel activity in men with metastatic castration-resistant prostate cancer with and without DNA damage repair defects
Abstract
Cabazitaxel was shown to improve overall survival (OS) in patients with metastatic castration-resistant prostate cancer (mCRPC) after abiraterone/enzalutamine and docetaxel failure, though benefit by the presence of DNA damage repair (DDR) defects is unknown. With the advent of poly(adenosine diphosphate-ribose) polymerase inhibitors (PARPi) in partially overlapping indications with cabazitaxel, we aimed to determine cabazitaxel activity in men...
Paper Details
Title
Cabazitaxel activity in men with metastatic castration-resistant prostate cancer with and without DNA damage repair defects
Published Date
Dec 1, 2021
Journal
Volume
159
Pages
87 - 97
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