Original paper
First synthesis of tabamides A–C and their derivatives: In vitro nitric oxide inhibitory activity
Abstract
The first synthesis of natural phenolic amides, tabamides A–C (1–3), and their derivatives (4–12) was accomplished using Stobbe condensation and amide coupling reactions as key steps. The in vitro nitric oxide (NO) inhibitory effects of these compounds in LPS-induced RAW-264.7 macrophages were evaluated as an indicator of anti-inflammatory activity. All compounds tested had a concentration-dependent inhibitory effect on NO production by...
Paper Details
Title
First synthesis of tabamides A–C and their derivatives: In vitro nitric oxide inhibitory activity
Published Date
Nov 1, 2021
Journal
Volume
85
Pages
153482 - 153482
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Notes
History