MALAT1 promotes liver fibrosis by sponging miR‑181a and activating TLR4‑NF‑κB signaling

Volume: 48, Issue: 6
Published: Oct 13, 2021
Abstract
The aim of the present study was to investigate whether long non‑coding RNA metastasis associated lung adenocarcinoma transcript 1 (MALAT1) could modulate activation and inflammation of hepatic stellate cell (HSCs) via regulation of a microRNA (miR)‑181a‑toll like receptor (TLR)4/nuclear factor (NF)‑κB axis, thereby contributing to the development of liver fibrosis. A total of 151 patients with liver fibrosis were recruited, and the serum levels...
Paper Details
Title
MALAT1 promotes liver fibrosis by sponging miR‑181a and activating TLR4‑NF‑κB signaling
Published Date
Oct 13, 2021
Volume
48
Issue
6
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