Preparation and Evaluation of Self-emulsifying Drug Delivery System (SEDDS) of Cepharanthine
Abstract
The aim of this article was to design a self-emulsifying drug delivery system (SEDDS) of loaded cepharanthine (CEP) to improve the oral bioavailability in rats. Based on the solubility determination and pseudo-ternary phase diagram, isopropyl palmitate (IPP) was chosen as the oil phase. Meanwhile, Cremophor RH40 and Macrogol 200 (PEG 200) were chosen as the emulsifier and co-emulsifier, respectively. This prescription was further optimized by...
Paper Details
Title
Preparation and Evaluation of Self-emulsifying Drug Delivery System (SEDDS) of Cepharanthine
Published Date
Oct 1, 2021
Journal
Volume
22
Issue
7
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