Inhaled corticosteroid dose is associated with Pseudomonas aeruginosa infection in severe COPD

Introduction Patients with chronic obstructive pulmonary disease (COPD) with frequent exacerbations (ExCOPD) are commonly treated with inhaled corticosteroids (ICS) and are at risk of infections caused by potential pathogenic bacteria (PPB) including Pseudomonas aeruginosa (PsA). Objectives To investigate the association between the use of ICS and PsA infection among ExCOPD. Methods Case–control study with longitudinal follow-up that recruited...