Original paper
Fission yeast RNA‐binding proteins Puf2 and Puf4 are involved in repression of ferrireductase Frp1 expression in response to iron
Abstract
This study identifies a post‐transcriptional mechanism of iron uptake regulation by Puf2 and Puf4 of the Pumilio and FBF (Puf) family of RNA‐binding proteins in Schizosaccharomyces pombe . Cells expressing Puf2 and Puf4 stimulate decay of the frp1 + mRNA encoding a key enzyme of the reductive iron uptake pathway. Results consistently showed that frp1 + mRNA is stabilized in puf2Δ puf4Δ mutant cells under iron‐replete conditions. As a result,...
Paper Details
Title
Fission yeast RNA‐binding proteins Puf2 and Puf4 are involved in repression of ferrireductase Frp1 expression in response to iron
Published Date
Oct 21, 2021
Journal
Volume
116
Issue
5
Pages
1361 - 1377
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Notes
History