Renal Clearance of FGF23 and its Fragments in Humans
Abstract
Background: Relative abundance of fibroblast growth factor-23 (FGF23) measured by the C-terminal (cFGF23, which measures both intact FGF23 & c-terminal fragments) vs intact (iFGF23, measures only intact hormone) assays varies by kidney function in humans. Differential kidney clearance may explain this.
Methods: We measured cFGF23 and iFGF23 in the aorta and bilateral renal veins of 162 patients with essential hypertension undergoing renal...
Paper Details
Title
Renal Clearance of FGF23 and its Fragments in Humans
Published Date
Jan 1, 2021
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