Original paper
Botulinum toxin A promotes the transdifferentiation of primary keloid myofibroblasts into adipocyte‐like cells
Volume: 129, Issue: 6, Pages: 462 - 469
Published: Oct 20, 2021
Abstract
Keloid is a type of unusually raised scar. Botulinum toxin A (BTX-A) has a great application potential in keloids treatment. Here, we investigated the functional role of BTX-A in keloids. We separated keloid tissues and normal skin tissues from keloid patients and found that the expression of myofibroblast markers, α-SMA, Collagen I, and Collagen III was increased in the keloid tissues as compared with normal skin tissues. Keloid fibroblasts...
Paper Details
Title
Botulinum toxin A promotes the transdifferentiation of primary keloid myofibroblasts into adipocyte‐like cells
Published Date
Oct 20, 2021
Volume
129
Issue
6
Pages
462 - 469
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Notes
History