Primary aldosteronism diagnosis: is cosyntropin stimulation in adrenal venous sampling still convincing?

Primary aldosteronism is now recognized as the most frequent form of secondary hypertension, characterized by a higher burden of organ damage compared with primary hypertension. Once diagnosed, targeted therapy leads to control of hypertension, resolution of hypokalaemia, and reverses increased cardiovascular risk. In the last two decades, awareness of the importance of a correct diagnosis has progressively increased, mirrored by a consensual...