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doi.org/10.1126/scitranslmed.abj1578
Original paper

A selective WDR5 degrader inhibits acute myeloid leukemia in patient-derived mouse models

..., Jian Jin
64
Science Translational Medicine15.80
Volume: 13, Issue: 613
Published: Sep 29, 2021
Abstract
WDR5-degrader-E3 ligase ternary complex structure–based design led to a highly effective WDR5 degrader with robust in vivo antitumor...
Paper Fields
Paper Details
Title
A selective WDR5 degrader inhibits acute myeloid leukemia in patient-derived mouse models
DOI
doi.org/10.1126/scitranslmed.abj1578
Published Date
Sep 29, 2021
Journal
Science Translational Medicine
Volume
13
Issue
613
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