Reductive electrophilic C–H alkylation of quinolines by a reusable iridium nanocatalyst

The incorporation of a coupling step into the reduction of unsaturated systems offers a desirable way for diverse synthesis of functional molecules, but it remains to date a challenge due to the difficulty in controlling the chemoselectivity. Herein, by developing a new heterogeneous iridium catalyst composed of Ir-species (Ir δ+) and N-doped SiO2/TiO2 support (Ir/N-SiO2/TiO2), we describe its application in reductive electrophilic mono and...