Original paper
Alteration of organ size and allometric scaling by organ-specific targeting of IGF signaling
Abstract
The size of an organ is proportional to the other body parts or the whole body. This relationship is known as allometry. Understanding how allometry is determined is a fundamental question in biology. Here we tested the hypothesis that local insulin-like growth factor (Igf) signaling is critical in regulating organ size and its allometric scaling by organ-specific expression of Igf binding protein (Igfbp). Overexpression of Igfbp2a or 5b in the...
Paper Details
Title
Alteration of organ size and allometric scaling by organ-specific targeting of IGF signaling
Published Date
Dec 1, 2021
Volume
314
Pages
113922 - 113922
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Notes
History