General and Comparative Endocrinology
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#1Karim Mahnam (Shahrekord University)H-Index: 11
#2Mostafa Shakhsi-Niaei (Shahrekord University)H-Index: 3
Last. Karen L. Sweazea (ASU: Arizona State University)H-Index: 14
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In contrast to mammals, glucagon is reported as a much more potent blood glucose modulator in birds. Interestingly, we have found p.Thr16Ser mutation, a variation in the highly conserved glucagon hormone, in Galliformes as well as Strigiformes. To check the effect of this mutation on the receptor binding of glucagon, we predicted the ancestral glucagon receptor sequence of all available Galliformes and Strigiformes species. Subsequently, we analysed their binding to the mutated and wild type glu...
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#1Timothy J. Greives (NDSU: North Dakota State University)H-Index: 22
#2Michelle A. Eshleman (NDSU: North Dakota State University)
Last. Michaela Hau (University of Konstanz)H-Index: 53
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Abstract null null Experimental manipulation has established testosterone as a potent, pleiotropic regulator coordinating morphology, physiology and behavior. However, the relationship of field-sampled, unmanipulated testosterone concentrations with traits of interest is often equivocal. Circulating testosterone varies over the course of the day, and recent reports indicate that testosterone is higher during the night in diurnal songbirds. Yet, most field studies sample testosterone during the m...
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#1Yong Zhu (ECU: East Carolina University)H-Index: 25
Abstract null null Changes in expression or activation of various metalloproteases including matrix metalloproteases (Mmp), a disintegrin and metalloprotease (Adam) and a disintegrin and metalloprotease with thrombospondin motif (Adamts), and their endogenous inhibitors (tissue inhibitors of metalloproteases, Timp), have been shown to be critical for ovulation in various species from studies in past decades. Some of these metalloproteases such as Adamts1, Adamts9, Mmp2, and Mmp9 have also been s...
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#1Hiroyasu Kamei (Kanazawa University)H-Index: 16
#2Cunming Duan (UM: University of Michigan)H-Index: 52
The size of an organ is proportional to the other body parts or the whole body. This relationship is known as allometry. Understanding how allometry is determined is a fundamental question in biology. Here we tested the hypothesis that local insulin-like growth factor (Igf) signaling is critical in regulating organ size and its allometric scaling by organ-specific expression of Igf binding protein (Igfbp). Overexpression of Igfbp2a or 5b in the developing zebrafish eye, heart, and inner ear resu...
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#1Bettina Lanfranchi (UZH: University of Zurich)
#2Ricardo Fernandez Rubia (UZH: University of Zurich)
Last. Mariusz P. Kowalewski (UZH: University of Zurich)H-Index: 24
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Gonadal function is connected to hypoxia, with hypoxia-inducible factor (HIF) 1α, as a component of HIF1-complexes, regulating cellular adaptation to hypoxic conditions. In the ovary, it regulates follicular maturation, ovulation and luteal development. At the cellular level, HIF1-complexes coordinate the expression of steroidogenic acute regulatory protein (STAR), and thereby ovarian steroidogenesis. The functionality of STAR is associated with the cAMP/PKA-dependent pathways. In vitro, HIF1α i...
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#1Norma Berenice Cruz-Cano (UNAM: National Autonomous University of Mexico)H-Index: 1
#2Uriel Ángel Sánchez-Rivera (UNAM: National Autonomous University of Mexico)H-Index: 1
Last. Martín Martínez-Torres (UNAM: National Autonomous University of Mexico)H-Index: 5
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Reproduction is regulated by multiple factors that influence physiology and behavior to ensure the continuity of species. However, more work is needed to examine the complex relationships between environmental factors and endocrine transducers that modulate reproductive cycles, particularly in lizards. Here, we aimed to characterize the variation in plasma sex steroid levels in different stages of the reproductive cycle in the lizard Sceloporus torquatus and assess whether sex steroid levels wer...
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#1Kathryn A. Shutt-Phillips (World Conservation Monitoring Centre)H-Index: 1
#2Barbora Pafčo (CAS: Academy of Sciences of the Czech Republic)H-Index: 7
Last. Jean-Francais DickyH-Index: 1
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Abstract null null Wildlife ecotourism can offer a source of revenue which benefits local development and conservation simultaneously. However, habituation of wildlife for ecotourism can cause long-term elevation of glucocorticoid hormones, which may suppress immune function and increase an animal’s vulnerability to disease. We have previously shown that western lowland gorillas (Gorilla gorilla gorilla) undergoing habituation in Dzanga-Sangha Protected Areas, Central African Republic, have high...
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#1Ying-Jey Guh (AS: Academia Sinica)H-Index: 3
#2Yung-Che Tseng (AS: Academia Sinica)H-Index: 17
Last. Yi Ta Shao (NTOU: National Taiwan Ocean University)H-Index: 9
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Abstract null null Anthropogenic underwater noises that change aquatic soundscapes represent an important issue in marine conservation. While it is evident that strong underwater acoustic pollutants may cause significant damage to fish at short ranges, the physiological effects of long-term exposure to relatively quiet but continuous noise are less well understood. Here, we present a summary of the known impacts of long-term underwater noise on hypothalamic-pituitary-interrenal (HPI) axis-mediat...
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#1Chloe C Josefson (UIdaho: University of Idaho)H-Index: 3
#2A.L. Skibiel (UIdaho: University of Idaho)
Abstract null null Maternal exposure to stressors during lactation has previously been demonstrated to impact various aspects of milk synthesis and to have long-term physiological effects on offspring. Much of the current literature investigating the effects of stress during lactation has used acute stressors, and the studies investigating the effects of chronic stressors largely focus on neurological changes. Further, temporal variation in glucocorticoids across lactation in response to stresso...
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#1Shinji Tsukahara (Saitama University)H-Index: 19
#2Masahiro Morishita (Saitama University)H-Index: 5
Last. Takaharu Kawashima (National Institute for Environmental Studies)H-Index: 7
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Japanese quail (Coturnix japonica) is an avian model used to evaluate the reproductive and developmental toxicity of chemicals. The National Institute for Environmental Studies (NIES) of Japan established a strain of Japanese quail, NIES-L, which may be a better model because of its highly inbred characteristics. To understand sexual differentiation of the reproductive organs and the value of using NIES-L quails for avian toxicity assessment, we profiled estradiol and androgen plasma levels by e...
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