Original paper
Triple reassortment increases compatibility among viral ribonucleoprotein genes of contemporary avian and human influenza A viruses
Abstract
Compatibility among the influenza A virus (IAV) ribonucleoprotein (RNP) genes affects viral replication efficiency and can limit the emergence of novel reassortants, including those with potential pandemic risks. In this study, we determined the polymerase activities of 2,451 RNP reassortants among three seasonal and eight enzootic IAVs by using a minigenome assay. Results showed that the 2009 H1N1 RNP are more compatible with the tested...
Paper Details
Title
Triple reassortment increases compatibility among viral ribonucleoprotein genes of contemporary avian and human influenza A viruses
Published Date
Oct 7, 2021
Journal
Volume
17
Issue
10
Pages
e1009962 - e1009962
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Notes
History