Original paper
A conserved and seemingly redundant Escherichia coli biotin biosynthesis gene expressed only during anaerobic growth
Abstract
Biotin is an essential metabolic cofactor and de novo biotin biosynthetic pathways are widespread in microorganisms and plants. Biotin synthetic genes are generally found clustered into bio operons to facilitate tight regulation since biotin synthesis is a metabolically expensive process. Dethiobiotin synthetase (DTBS) catalyzes the penultimate step of biotin biosynthesis, the formation of 7,8-diaminononanoate (DAPA). In Escherichia coli, DTBS...
Paper Details
Title
A conserved and seemingly redundant Escherichia coli biotin biosynthesis gene expressed only during anaerobic growth
Published Date
Oct 18, 2021
Journal
Volume
116
Issue
5
Pages
1315 - 1327
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Notes
History