Original paper
Does timing matter in radiotherapy of hepatocellular carcinoma? An experimental study in mice
Abstract
This study investigates whether a chronotherapeutic treatment of hepatocellular carcinoma (HCC) may improve treatment efficacy and mitigate side effects on non-tumoral liver (NTL). HCC was induced in Per2::luc mice which were irradiated at four time points of the day. Proliferation and DNA-double strand breaks were analyzed in irradiated and nonirradiated animals by detection of Ki67 and γ-H2AX. Prior to whole animal experiments, organotypic...
Paper Details
Title
Does timing matter in radiotherapy of hepatocellular carcinoma? An experimental study in mice
Published Date
Sep 20, 2021
Journal
Volume
10
Issue
21
Pages
7712 - 7725
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Notes
History