Original paper
Bioengineered 3D models of human pancreatic cancer recapitulate in vivo tumour biology
Abstract
Patient-derived in vivo models of human cancer have become a reality, yet their turnaround time is inadequate for clinical applications. Therefore, tailored ex vivo models that faithfully recapitulate in vivo tumour biology are urgently needed. These may especially benefit the management of pancreatic ductal adenocarcinoma (PDAC), where therapy failure has been ascribed to its high cancer stem cell (CSC) content and high density of stromal cells...
Paper Details
Title
Bioengineered 3D models of human pancreatic cancer recapitulate in vivo tumour biology
Published Date
Sep 24, 2021
Journal
Volume
12
Issue
1
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Notes
History