HOPX+ injury-resistant intestinal stem cells drive epithelial recovery after severe intestinal ischemia
Volume: 321, Issue: 5, Pages: G588 - G602
Published: Nov 1, 2021
Abstract
Intestinal ischemia is a life-threatening emergency with mortality rates of 50%-80% due to epithelial cell death and resultant barrier loss. Loss of the epithelial barrier occurs in conditions including intestinal volvulus and neonatal necrotizing enterocolitis. Survival depends on effective epithelial repair; crypt-based intestinal epithelial stem cells (ISCs) are the source of epithelial renewal in homeostasis and after injury. Two ISC...
Paper Details
Title
HOPX+ injury-resistant intestinal stem cells drive epithelial recovery after severe intestinal ischemia
Published Date
Nov 1, 2021
Volume
321
Issue
5
Pages
G588 - G602
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