Adrenaline effects on cerebral physiology during cardiac arrest: More to this story

Clinicians want to know: does adrenaline administration during CPR improve hemodynamics and outcomes? Adrenaline (epinephrine) has been recommended during CPR for the last five decades, in large part based on foundational translational animal studies that established improvements in coronary perfusion pressure (CoPP), cerebral perfusion pressure (CePP), myocardial blood flow, cerebral blood flow (CBF), survival, and survival with favorable...