Association and Interaction of TOMM40 and PVRL2 with Plasma Amyloid-Β and Alzheimer's Disease Among Chinese Older Adults: A Population-Based Study
Abstract
Background: Despite genetic studies have identified Alzheimer’s disease (AD)-associated SNPs in TOMM40 and PVRL2 genes, the underlying mechanisms have not yet been elucidated. We examined their associations and interactions with AD risk and plasma AD biomarkers among Chinese older adults.
Methods: This population-based study included 4876 participants (age ≥65 years, 57.2% women) from the MIND-China study. TOMM40(rs2075650) and PVRL2(rs6859)...
Paper Details
Title
Association and Interaction of TOMM40 and PVRL2 with Plasma Amyloid-Β and Alzheimer's Disease Among Chinese Older Adults: A Population-Based Study
Published Date
Jan 1, 2021
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