Review paper
Cell transdifferentiation in ocular disease: Potential role for connexin channels
Abstract
Cell transdifferentiation is the conversion of a cell type to another without requiring passage through a pluripotent cell state, and encompasses epithelial- and endothelial-mesenchymal transition (EMT and EndMT). EMT and EndMT are well defined processes characterized by a loss of epithelial/endothelial phenotype and gain in mesenchymal spindle shaped morphology, which results in increased cell migration and decreased apoptosis and cellular...
Paper Details
Title
Cell transdifferentiation in ocular disease: Potential role for connexin channels
Published Date
Oct 1, 2021
Journal
Volume
407
Issue
2
Pages
112823 - 112823
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