ATM’s Role in the Repair of DNA Double-Strand Breaks
Abstract
Ataxia telangiectasia mutated (ATM) is a central kinase that activates an extensive network of responses to cellular stress via a signaling role. ATM is activated by DNA double strand breaks (DSBs) and by oxidative stress, subsequently phosphorylating a plethora of target proteins. In the last several decades, newly developed molecular biological techniques have uncovered multiple roles of ATM in response to DNA damage-e.g., DSB repair, cell...
Paper Details
Title
ATM’s Role in the Repair of DNA Double-Strand Breaks
Published Date
Aug 31, 2021
Journal
Volume
12
Issue
9
Pages
1370 - 1370
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