Tumor deposits improve staging in colon cancer: what are the next steps?

Traditionally, lymph node metastases (LNM) play a crucial part in the staging of colon cancer patients according to the TNM (tumor–node–metastasis) system, which is based on the prevailing hypothesis that metastatic disease is the direct result of lymphatic spread.1Dukes C.E. The classification of cancer of the rectum.J Pathol Bacteriol. 1932; 35: 323-332Crossref Google Scholar In recent years, however, studies have shown that other types of...